Now here's a study that should make most seasoned molecular modelers cringe. Nature News reports on an effort by website Drugable.com that docked 600,000 compounds to 7,000 protein targets and predicted which ones would show activity against these targets based on docking scores:Predicting how untested compounds will interact with proteins in the body, as Drugable attempts to do, is more challenging. In setting up the website, Cardozo’s group selected about 600,000 molecules from PubChem
Sam Stephenson at The Paris Review: In early March of 1955, W. Eugene Smith steered his overstuffed station wagon into the steel city of Pittsburgh. He’d been on the road all day, leaving that morning from Croton-on-Hudson, New York, where...
An international team of astronomers using NASA’s Hubble Space Telescope has discovered strong evidence of giant water-vapor geysers shooting off of Europa, the smallest of Jupiter’s Galilean moons. “Water is generally considered a basic prerequisite for life – at least as we know it on Earth. For this reason, the discovery of a water vapor [...]
We haven’t had one of these in awhile, having mostly switched to the “chess trivia” and “bad p-values” genres of blogging . . . But I had to come back to the topic after receiving this note from Raghuveer Parthasarathy: Here’s another bad graph you might like. It might (arguably) be even worse than the […]The post And now, here’s something that would make Ed Tufte spin in his . . . ummm, Tufte’s still around, actually, so let’s just