A new study finds that a new cancer drug restores memory in mouse model of Alzheimer’s disease. Alzheimer’s disease is a form of progressive dementia affecting more than 10% of Americans over the age of 65. It’s predicted that the disease will affect more than 3 million people aged 85 and older in the coming decades. Even more disappointing is the fact that so many trials for new drugs to treat the disease fail. Between 2002 and 2013 413 drug trials were
It’s the last trumpet. It’s been an intense few months up on the Ridgeway; preparations for our big change have gathered pace. At first things went slowly – infuriatingly slowly – but as the years crept on so we felt … Continue reading →
There’s a lovely review in Nature Methods this week from James Fraser (UCSF) and Henry van den Bedem (Stanford).
It’s about time — the time course of protein motions (their pun not mine!), acknowledging “that dynamically exchanging networks are a macromolecule’s evolutionary unit”.
Recent advances in X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy and other techniques are helping us realize the dream of seeing—in atomic